Behind the science
Creatine for Women: Benefits, Menopause Support and What You Should Know
Herbalife 4 April 2025
What Does Creatine Do?
Creatine helps regenerate ATP (adenosine triphosphate), the body’s rapid energy source for short bursts of high-intensity activity such as resistance training, sprinting and HIIT.
Creatine is scientifically proven to help energy production in successive bursts of short-term, high-intensity exercise.¹
Do Women Benefit from Creatine as Much as Men?
Women naturally have around 20–30% lower intramuscular creatine stores compared to men.²
However, research indicates that women respond just as effectively to creatine supplementation, experiencing similar improvements in strength and performance.¹
Importantly, these improvements can occur even without significant changes in total body weight.¹
Will Creatine Make Women Gain Weight?
When used alongside resistance training, creatine has been shown to support increases in lean muscle mass.*˒³
While creatine could in some cases lead to insignificant weight gain it does so without increasing fat mass.⁴⁻⁸
*For this effect it is necessary to load with ~20 grams per day for 5-7 days and maintaining at 3-5 grams per day after.
Is Creatine Safe for Women?
Creatine monohydrate is one of the most researched sports supplements available³. Studies assessing the long-term intake of creatine supplements concluded it is well-tolerated and safe.⁹
Current evidence does not indicate that creatine negatively affects hormonal balance or menstrual function in women.
As with any supplement, individuals with underlying medical conditions should consult a healthcare professional before use.¹˒³˒⁹˒¹⁰
Can Creatine Help During Menopause?
Age-related declines in oestrogen are associated with reductions in muscle mass and strength.⁸˒¹¹
Research suggests that creatine supplementation — particularly when combined with resistance training — may help support muscle strength and functional capacity in older and post-menopausal women.**˒¹
Given the importance of maintaining muscle mass for mobility, metabolic health and independence later in life, this is an area of growing scientific interest.
**For this effect it is necessary to load with ~20 grams per day for 5-7 days and maintaining at 5 grams per day after.
How Much Creatine Should Women Take?
For most healthy adult women:
- Loading phase: ~20 g per day (split into doses) for 5–7 days¹⁰
- Maintenance dose: 3–5 g per day¹⁰
Alternatively, taking at least 3 grams per day for at least 28 days.
How Long Does Creatine Take to Work?
With a loading phase, muscle creatine stores increase rapidly within 5–7 days.⁵
With steady loading, daily supplementation of 3–5 g typically elevates muscle creatine levels in about 4 weeks.¹⁰
Improvements in strength and high-intensity performance may become noticeable within a few weeks after the loading phase when combined with structured training.³
The Bottom Line
Creatine is not just a supplement for male athletes.
Research shows it can support strength, performance and muscle maintenance in women — including during later life stages — when combined with resistance training and a balanced lifestyle.¹˒¹⁰
Disclaimer
Whilst we strive to provide reliable and accurate information, the content in this article is for information only and should not replace medical care. Please consult a medical professional or GP to discuss your nutritional needs before trying any supplements. Food supplements must not be used as a substitute for a balanced and healthy diet and lifestyle.
References
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- Burke R, et al. Nutrients. 2023;15(9):2116.
- Antonio J, et al. J Int Soc Sports Nutr. 2021;18:1-17.
- Pashayee-Khamene F, et al. J Int Soc Sports Nutr. 2024;21(1):2380058.
- Collins BC, et al. Bone. 2019;123:137-44.
- Kreider RB, et al. Journal of the International Society of Sports Nutrition. 2017;14(1):18.
- Shao A, et al. Regulatory Toxicology and Pharmacology. 2006;45(3):242–251.
- Messier V, et al. Maturitas. 2011;68(4):331-6