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Behind the science

Creatine for Women: Benefits, Menopause Support and What You Should Know

​​Herbalife​ 4 April 2025

What Does Creatine Do?

Creatine helps regenerate ATP (adenosine triphosphate), the body’s rapid energy source for short bursts of high-intensity activity such as resistance training, sprinting and HIIT.

 

Creatine is scientifically proven to help energy production in successive bursts of short-term, high-intensity exercise.¹

Do Women Benefit from Creatine as Much as Men?

Women naturally have around 20–30% lower intramuscular creatine stores compared to men.²

 

However, research indicates that women respond just as effectively to creatine supplementation, experiencing similar improvements in strength and performance.¹

 

Importantly, these improvements can occur even without significant changes in total body weight.¹

Will Creatine Make Women Gain Weight?

When used alongside resistance training, creatine has been shown to support increases in lean muscle mass.*˒³ 

 

While creatine could in some cases lead to insignificant weight gain it does so without increasing fat mass.⁴⁻⁸

 

*For this effect it is necessary to load with ~20 grams per day for 5-7 days and maintaining at 3-5 grams per day after.

Is Creatine Safe for Women?

Creatine monohydrate is one of the most researched sports supplements available³. Studies assessing the long-term intake of creatine supplements concluded it is well-tolerated and safe.⁹

 

Current evidence does not indicate that creatine negatively affects hormonal balance or menstrual function in women.

 

As with any supplement, individuals with underlying medical conditions should consult a healthcare professional before use.¹˒³˒⁹˒¹⁰

Can Creatine Help During Menopause?

Age-related declines in oestrogen are associated with reductions in muscle mass and strength.⁸˒¹¹

 

Research suggests that creatine supplementation — particularly when combined with resistance training — may help support muscle strength and functional capacity in older and post-menopausal women.**˒¹

 

Given the importance of maintaining muscle mass for mobility, metabolic health and independence later in life, this is an area of growing scientific interest.


**For this effect it is necessary to load with ~20 grams per day for 5-7 days and maintaining at 5 grams per day after.

How Much Creatine Should Women Take?

For most healthy adult women:

 

  • Loading phase: ~20 g per day (split into doses) for 5–7 days¹⁰
  • Maintenance dose: 3–5 g per day¹⁰

Alternatively, taking at least 3 grams per day for at least 28 days. 

 

How Long Does Creatine Take to Work?

With a loading phase, muscle creatine stores increase rapidly within 5–7 days.⁵ 


With steady loading, daily supplementation of 3–5 g typically elevates muscle creatine levels in about 4 weeks.¹⁰ 

 

Improvements in strength and high-intensity performance may become noticeable within a few weeks after the loading phase when combined with structured training.³

The Bottom Line

Creatine is not just a supplement for male athletes. 

 

Research shows it can support strength, performance and muscle maintenance in women — including during later life stages — when combined with resistance training and a balanced lifestyle.¹˒¹⁰

Disclaimer

Whilst we strive to provide reliable and accurate information, the content in this article is for information only and should not replace medical care. Please consult a medical professional or GP to discuss your nutritional needs before trying any supplements. Food supplements must not be used as a substitute for a balanced and healthy diet and lifestyle.

References

  1. Smith-Ryan AE, et al. Nutrients. 2021;13(3).
  2. Brosnan JT, et al. Annual Review of Nutrition. 2007;27:241–261.
  3. Kerksick CM, et al. Journal of the International Society of Sports Nutrition. 2018;15(1):38.
  4. Candow DG, et al. Nutrients. 2023;15(20):4343. 
  5. Burke R, et al. Nutrients. 2023;15(9):2116.
  6. Antonio J, et al. J Int Soc Sports Nutr. 2021;18:1-17.
  7. Pashayee-Khamene F, et al. J Int Soc Sports Nutr. 2024;21(1):2380058.
  8. Collins BC, et al. Bone. 2019;123:137-44. 
  9. Kreider RB, et al. Journal of the International Society of Sports Nutrition. 2017;14(1):18.
  10. Shao A, et al. Regulatory Toxicology and Pharmacology. 2006;45(3):242–251.
  11. Messier V, et al. Maturitas. 2011;68(4):331-6